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Assay Detail

CHEMBL4138803

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of L3MBTL1 (unknown origin) by AlphaScreen assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lethal(3)malignant brain tumor-like protein 1 (CHEMBL1287622)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Methyllysine binding domains: Structural insight and small molecule probe development.
Teske KA, Hadden MK.
Eur J Med Chem (2017) 136 : 14 -35
PubMed 28478342 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.78 7.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3351077 CEFSULODIN 2.0 1 7.01
CHEMBL1257003 1 6.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3351077 CEFSULODIN IC50 = 98.0 nM 7.01
CHEMBL1257003 IC50 = 282.0 nM 6.55