Assay Detail
ADMET
CHEMBL4138876
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Cytotoxicity against human HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New cycloartane type-triterpenoids from the areal parts of Caragana sukiensis and their biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.05 | 4.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4163320 | — | — | 1 | 4.10 |
| CHEMBL4159948 | — | — | 1 | 4.10 |
| CHEMBL455098 | beta-AMYRIN | — | 1 | 4.03 |
| CHEMBL4170605 | — | — | 1 | 4.02 |
| CHEMBL500607 | — | — | 1 | 4.00 |
| CHEMBL4161461 | — | — | 1 | - |
| CHEMBL4171223 | — | — | 1 | - |
| CHEMBL4167864 | — | — | 1 | - |
| CHEMBL4175075 | — | — | 1 | - |
| CHEMBL4171632 | — | — | 1 | - |
| CHEMBL4161026 | — | — | 1 | - |
| CHEMBL1762007 | SOYASAPOGENOL B | — | 1 | - |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4163320 | — | IC50 | = | 79170.0 | nM | 4.10 |
| CHEMBL4159948 | — | IC50 | = | 79330.0 | nM | 4.10 |
| CHEMBL455098 | beta-AMYRIN | IC50 | = | 94400.0 | nM | 4.03 |
| CHEMBL4170605 | — | IC50 | = | 95600.0 | nM | 4.02 |
| CHEMBL500607 | — | IC50 | = | 99400.0 | nM | 4.00 |
| CHEMBL4161461 | — | IC50 | = | 123000.0 | nM | - |
| CHEMBL4171223 | — | IC50 | = | 167300.0 | nM | - |
| CHEMBL4167864 | — | IC50 | = | 158000.0 | nM | - |
| CHEMBL4175075 | — | IC50 | = | 120700.0 | nM | - |
| CHEMBL4171632 | — | IC50 | = | 127700.0 | nM | - |
| CHEMBL4161026 | — | IC50 | = | 121200.0 | nM | - |
| CHEMBL1762007 | SOYASAPOGENOL B | IC50 | = | 123700.0 | nM | - |
| CHEMBL53463 | DOXORUBICIN | IC50 | - | — | - |