Assay Detail
Functional
CHEMBL4144046
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Antiproliferative activity against human CCRF-CEM cells after 72 hrs by Cell-TiterGlo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.74 | 5.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4168815 | — | — | 1 | 5.87 |
| CHEMBL2132936 | — | — | 1 | 5.69 |
| CHEMBL4177080 | — | — | 1 | 5.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4168815 | — | EC50 | = | 1365.0 | nM | 5.87 |
| CHEMBL2132936 | — | EC50 | = | 2037.0 | nM | 5.69 |
| CHEMBL4177080 | — | EC50 | = | 2221.0 | nM | 5.65 |