Assay Detail
Functional
CHEMBL4145266
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Antagonist activity at 5-HT2B (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.36 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4168125 | — | — | 1 | 7.05 |
| CHEMBL4173963 | — | — | 1 | 6.64 |
| CHEMBL4159471 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4168125 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL4173963 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL4159471 | — | IC50 | = | 4000.0 | nM | 5.40 |