Assay Detail
Functional
CHEMBL4146135
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Growth inhibition of Plasmodium knowlesi YH1 after 50 hrs by ethidium bromide staining based flow cytometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium knowlesi |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.05 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4166227 | — | — | 1 | 7.10 |
| CHEMBL4174142 | — | — | 1 | 7.10 |
| CHEMBL4165957 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4166227 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL4174142 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL4165957 | — | IC50 | = | 110.0 | nM | 6.96 |