Assay Detail
Functional
CHEMBL4146887
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Inhibition of pigmentation in methicillin-resistant Staphylococcus aureus USA400 MW2 after 48 hrs by spectrophotometric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.17 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4161555 | — | — | 1 | 8.21 |
| CHEMBL4162120 | — | — | 1 | 8.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4161555 | — | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL4162120 | — | IC50 | = | 7.6 | nM | 8.12 |