Assay Detail
Functional
CHEMBL4147068
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against BVDV NADL ATCC VR-534 infected in MDBK cells assessed as protection against virus-induced cytopathic effect after 3 to 4 days by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bovine viral diarrhea virus 1-NADL |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Bovine viral diarrhea virus 1 (CHEMBL612571) ↗| Type | ORGANISM |
| Organism | Bovine viral diarrhea virus 1 |
Publication
Quinoxaline derivatives as new inhibitors of coxsackievirus B5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 5.48 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418899 | 2'-B-METHYL-GUANOSINE | — | 1 | 5.96 |
| CHEMBL4165162 | — | — | 1 | 5.00 |
| CHEMBL4170313 | — | — | 1 | - |
| CHEMBL4159682 | — | — | 1 | - |
| CHEMBL4173766 | — | — | 1 | - |
| CHEMBL4163061 | — | — | 1 | - |
| CHEMBL4163461 | — | — | 1 | - |
| CHEMBL4171360 | — | — | 1 | - |
| CHEMBL4168581 | — | — | 1 | - |
| CHEMBL4160658 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418899 | 2'-B-METHYL-GUANOSINE | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4165162 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4170313 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4159682 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4173766 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4163061 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4163461 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4171360 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4168581 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4160658 | — | EC50 | > | 100000.0 | nM | - |