Assay Detail
Functional
CHEMBL4149477
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human KB/VJ300 cells after 72 hrs in presence of 0.1 uM of vincristine by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB/VJ300 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ajmaline, Oxindole, and Cytotoxic Macroline-Akuammiline Bisindole Alkaloids from Alstonia penangiana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.53 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6966 | VERAPAMIL | 4.0 | 1 | 7.00 |
| CHEMBL4161622 | — | — | 1 | 6.05 |
| CHEMBL4169538 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6966 | VERAPAMIL | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4161622 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL4169538 | — | IC50 | > | 10000.0 | nM | - |