Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4149604

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human ACHN cells after 72 hrs by CCK8 assay
10
Total Activities
10
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ACHN
Confidence 1 — Organism
Curated By Intermediate

Target

ACHN (CHEMBL614519)
Type CELL-LINE
Organism Homo sapiens

Publication

Cytotoxic and Antibacterial Eremophilane Sesquiterpenes from the Marine-Derived Fungus Cochliobolus lunatus SCSIO41401.
Fang W, Wang J, Wang J, Shi L, Li K, Lin X, Min Y, Yang B, Tang L, Liu Y, Zhou X.
J Nat Prod (2018) 81 : 1405 -1410
PubMed 29786436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 5.20 5.51
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4171739 1 5.51
CHEMBL1336 SORAFENIB 4.0 1 5.46
CHEMBL4160097 1 5.37
CHEMBL4168887 1 4.47
CHEMBL4170405 1 -
CHEMBL4163855 1 -
CHEMBL4160948 1 -
CHEMBL4164350 1 -
CHEMBL289277 EMODIN 1 -
CHEMBL509319 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4171739 IC50 = 3100.0 nM 5.51
CHEMBL1336 SORAFENIB IC50 = 3500.0 nM 5.46
CHEMBL4160097 IC50 = 4300.0 nM 5.37
CHEMBL4168887 IC50 = 34000.0 nM 4.47
CHEMBL4170405 IC50 > 50000.0 nM -
CHEMBL4163855 IC50 > 50000.0 nM -
CHEMBL4160948 IC50 > 50000.0 nM -
CHEMBL4164350 IC50 > 50000.0 nM -
CHEMBL289277 EMODIN IC50 - -
CHEMBL509319 Activity - -