Assay Detail
Functional
CHEMBL4152408
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production pretreated for 1 hr followed by LPS addition and measured after 24 hrs by Griess assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BV-2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-inflammatory effects of flavonoids in neurodegenerative disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.92 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL128000 | BUTEIN | — | 1 | 4.96 |
| CHEMBL31574 | FISETIN | 2.0 | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL128000 | BUTEIN | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL31574 | FISETIN | IC50 | = | 13500.0 | nM | 4.87 |