Assay Detail
ADMET
CHEMBL4153052
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Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.29 | 4.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167681 | — | — | 1 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167681 | — | IC50 | = | 51380.0 | nM | 4.29 |