Assay Detail
Functional
CHEMBL4153481
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Cytotoxicity against human PA-TU-8988T cells after 72 hrs under normoxic condition by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PaTu 8988t |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Syntheses and anti-pancreatic cancer activities of rakicidin A analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 6.31 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4171928 | — | — | 1 | 6.70 |
| CHEMBL3774991 | — | — | 1 | 6.62 |
| CHEMBL4161330 | — | — | 1 | 6.58 |
| CHEMBL4167966 | — | — | 1 | 6.52 |
| CHEMBL4171301 | — | — | 1 | 6.50 |
| CHEMBL4166855 | — | — | 1 | 6.44 |
| CHEMBL4167438 | — | — | 1 | 6.42 |
| CHEMBL3775684 | — | — | 1 | 6.35 |
| CHEMBL4162089 | — | — | 1 | 6.27 |
| CHEMBL4164532 | — | — | 1 | 6.19 |
| CHEMBL4174757 | — | — | 1 | 5.96 |
| CHEMBL4168578 | — | — | 1 | 5.85 |
| CHEMBL4175163 | — | — | 1 | 5.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4171928 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL3774991 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL4161330 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL4167966 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4171301 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL4166855 | — | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL4167438 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL3775684 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL4162089 | — | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL4164532 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL4174757 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4168578 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4175163 | — | IC50 | = | 2470.0 | nM | 5.61 |