Assay Detail
Functional
CHEMBL4153862
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human SW1736 cells after 96 hrs by SRB assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW-1736 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Targeting mitochondria: Esters of rhodamine B with triterpenoids are mitocanic triggers of apoptosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 6.04 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4160690 | — | — | 1 | 7.40 |
| CHEMBL4160108 | — | — | 1 | 6.82 |
| CHEMBL4164094 | — | — | 1 | 6.62 |
| CHEMBL4160966 | — | — | 1 | 6.57 |
| CHEMBL4165192 | — | — | 1 | 6.35 |
| CHEMBL4174175 | — | — | 1 | 6.13 |
| CHEMBL4176714 | — | — | 1 | 5.95 |
| CHEMBL4163693 | — | — | 1 | 5.76 |
| CHEMBL4170752 | — | — | 1 | 5.75 |
| CHEMBL4171970 | — | — | 1 | 5.19 |
| CHEMBL4162296 | — | — | 1 | 5.04 |
| CHEMBL4163475 | — | — | 1 | 4.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4160690 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4160108 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL4164094 | — | EC50 | = | 240.0 | nM | 6.62 |
| CHEMBL4160966 | — | EC50 | = | 270.0 | nM | 6.57 |
| CHEMBL4165192 | — | EC50 | = | 450.0 | nM | 6.35 |
| CHEMBL4174175 | — | EC50 | = | 740.0 | nM | 6.13 |
| CHEMBL4176714 | — | EC50 | = | 1130.0 | nM | 5.95 |
| CHEMBL4163693 | — | EC50 | = | 1720.0 | nM | 5.76 |
| CHEMBL4170752 | — | EC50 | = | 1760.0 | nM | 5.75 |
| CHEMBL4171970 | — | EC50 | = | 6430.0 | nM | 5.19 |
| CHEMBL4162296 | — | EC50 | = | 9050.0 | nM | 5.04 |
| CHEMBL4163475 | — | EC50 | = | 12660.0 | nM | 4.90 |