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Assay Detail

CHEMBL4155115

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitrypanosomal activity against Trypanosoma brucei brucei after 48 hrs by Alamar blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma brucei brucei
Confidence 1 — Organism
Curated By Intermediate

Target

Trypanosoma brucei brucei (CHEMBL612851)
Type ORGANISM
Organism Trypanosoma brucei brucei

Publication

Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent.
Ugwu DI, Okoro UC, Mishra NK.
Eur J Med Chem (2018) 154 : 110 -116
PubMed 29778893 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.92 6.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL55225 1 6.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL55225 IC50 = 120.0 nM 6.92