Assay Detail
Functional
CHEMBL4157372
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Antibacterial activity against multidrug resistant Staphylococcus aureus ATCC BAA-44 after 6 to 8 hrs
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 13 | 5.59 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4166077 | — | — | 1 | 6.28 |
| CHEMBL4161583 | — | — | 1 | 6.01 |
| CHEMBL4176697 | — | — | 1 | 5.96 |
| CHEMBL4167333 | — | — | 1 | 5.77 |
| CHEMBL4161487 | — | — | 1 | 5.70 |
| CHEMBL3970551 | — | — | 1 | 5.70 |
| CHEMBL4169499 | — | — | 1 | 5.66 |
| CHEMBL4160098 | — | — | 1 | 5.64 |
| CHEMBL3975683 | — | — | 1 | 5.46 |
| CHEMBL4168023 | — | — | 1 | 5.35 |
| CHEMBL4162794 | — | — | 1 | 5.34 |
| CHEMBL3955935 | — | — | 1 | 5.14 |
| CHEMBL4176281 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4166077 | — | EC50 | = | 530.0 | nM | 6.28 |
| CHEMBL4161583 | — | EC50 | = | 970.0 | nM | 6.01 |
| CHEMBL4176697 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4167333 | — | EC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL4161487 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL3970551 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4169499 | — | EC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL4160098 | — | EC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3975683 | — | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL4168023 | — | EC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL4162794 | — | EC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL3955935 | — | EC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL4176281 | — | EC50 | = | 19000.0 | nM | 4.72 |