Assay Detail
Binding
CHEMBL4157966
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Displacement of [3H]CP55940 from membrane bound human CB2 receptor after 1 hr by beta scintillation counting method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.20 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4166345 | — | — | 1 | 5.97 |
| CHEMBL4169849 | — | — | 1 | 5.77 |
| CHEMBL4161845 | — | — | 1 | 5.30 |
| CHEMBL244403 | — | — | 1 | 5.28 |
| CHEMBL4161451 | — | — | 1 | 4.90 |
| CHEMBL4167940 | — | — | 1 | 4.83 |
| CHEMBL4159535 | — | — | 1 | 4.32 |
| CHEMBL4176969 | — | — | 1 | - |
| CHEMBL4176556 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4166345 | — | IC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL4169849 | — | IC50 | = | 1690.0 | nM | 5.77 |
| CHEMBL4161845 | — | IC50 | = | 5050.0 | nM | 5.30 |
| CHEMBL244403 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL4161451 | — | IC50 | = | 12620.0 | nM | 4.90 |
| CHEMBL4167940 | — | IC50 | = | 14670.0 | nM | 4.83 |
| CHEMBL4159535 | — | IC50 | = | 47710.0 | nM | 4.32 |
| CHEMBL4176969 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4176556 | — | IC50 | > | 100000.0 | nM | - |