Assay Detail
Binding
CHEMBL4158628
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RSV Long fusion protein assessed as decrease in virus induced syncytium formation in infected human HeLa/M cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Respiratory syncytial virus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Fusion glycoprotein F0 (CHEMBL2364165) ↗| Type | SINGLE PROTEIN |
| Organism | Human respiratory syncytial virus |
Publication
Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally Bioavailable Respiratory Syncytial Virus Fusion Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 9.80 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL242456 | JNJ 2408068 | — | 1 | 9.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL242456 | JNJ 2408068 | EC50 | = | 0.16 | nM | 9.80 |