Assay Detail
Binding
CHEMBL4177794
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Inhibition of human MAGL
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.74 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3087181 | — | — | 1 | 9.44 |
| CHEMBL4216513 | — | — | 1 | 9.25 |
| CHEMBL4215558 | — | — | 1 | 7.54 |
| CHEMBL4207058 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3087181 | — | IC50 | = | 0.363 | nM | 9.44 |
| CHEMBL4216513 | — | IC50 | = | 0.562 | nM | 9.25 |
| CHEMBL4215558 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL4207058 | — | IC50 | > | 10000.0 | nM | - |