Assay Detail
Binding
CHEMBL4177817
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse MAGL
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.43 | 9.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4216513 | — | — | 1 | 9.72 |
| CHEMBL1232635 | — | — | 1 | 9.66 |
| CHEMBL3087181 | — | — | 1 | 9.56 |
| CHEMBL3356956 | — | — | 1 | 9.51 |
| CHEMBL4215558 | — | — | 1 | 8.42 |
| CHEMBL602499 | — | — | 1 | 6.55 |
| CHEMBL3356958 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4216513 | — | IC50 | = | 0.191 | nM | 9.72 |
| CHEMBL1232635 | — | IC50 | = | 0.219 | nM | 9.66 |
| CHEMBL3087181 | — | IC50 | = | 0.275 | nM | 9.56 |
| CHEMBL3356956 | — | IC50 | = | 0.309 | nM | 9.51 |
| CHEMBL4215558 | — | IC50 | = | 3.8 | nM | 8.42 |
| CHEMBL602499 | — | IC50 | = | 282.0 | nM | 6.55 |
| CHEMBL3356958 | — | IC50 | = | 2600.0 | nM | 5.58 |