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Assay Detail

CHEMBL4178561

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at human ERalpha expressed in yeast cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Estrogen receptor (CHEMBL206)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
Vuorinen A, Engeli RT, Leugger S, Bachmann F, Akram M, Atanasov AG, Waltenberger B, Temml V, Stuppner H, Krenn L, Ateba SB, Njamen D, Davis RA, Odermatt A, Schuster D.
J Nat Prod (2017) 80 : 965 -974
PubMed 28319389 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.67 7.67

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL312186 1 7.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL312186 EC50 = 21.4 nM 7.67