Assay Detail
Binding
CHEMBL4178949
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Inhibition of Bacillus cereus beta-lactamase AmpC using CENTA as substrate up to 30 mins by Lineweaver-Burk plot analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus cereus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Antibiotic adjuvants - A strategy to unlock bacterial resistance to antibiotics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.50 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209255 | — | — | 1 | 10.30 |
| CHEMBL4206040 | — | — | 1 | 9.70 |
| CHEMBL4217629 | — | — | 1 | 9.10 |
| CHEMBL4204887 | — | — | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209255 | — | Ki | = | 0.05 | nM | 10.30 |
| CHEMBL4206040 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL4217629 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL4204887 | — | Ki | = | 1.3 | nM | 8.89 |