Compound Detail
CHEMBL4217629
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Basic Information
| ChEMBL ID | CHEMBL4217629 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ALJNKILBJVRYAA-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
312.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 9.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-lactamase 1 CHEMBL5732 | Ki | 9.1 | 9.1 | 0.8 | 1 |
| Unchecked CHEMBL612545 | Ki | 9.1 | 9.1 | 0.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-lactamase 1 | Ki | = | 0.8 | nM | 9.1 | Inhibition of Bacillus cereus beta-lactamase AmpC using CENTA as substrate up to... | 28827113 |
| Unchecked | Ki | = | 0.8 | nM | 9.1 | Inhibition of AmpC beta-lactamase (unknown origin) by Cheng-Prusoff equation ana... | 31663735 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28827113 | 10.1016/j.bmcl.2017.08.027 | Beta-lactamase 1 | 1 |
| 31663735 | 10.1021/acs.jmedchem.9b01279 | Unchecked | 1 |
| 31663735 | 10.1021/acs.jmedchem.9b01279 | Escherichia coli | 1 |
Data from ChEMBL 36 via Core Engine