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Assay Detail

CHEMBL4403612

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AmpC beta-lactamase (unknown origin) by Cheng-Prusoff equation analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacteria
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

β-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs.
González-Bello C, Rodríguez D, Pernas M, Rodríguez Á, Colchón E.
J Med Chem (2020) 63 : 1859 -1881
PubMed 31663735 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 9.70 10.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4209255 1 10.30
CHEMBL4206040 1 9.70
CHEMBL4217629 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4209255 Ki = 0.05 nM 10.30
CHEMBL4206040 Ki = 0.2 nM 9.70
CHEMBL4217629 Ki = 0.8 nM 9.10