Assay Detail
Binding
CHEMBL4179169
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Displacement of [3H]prazosin from adrenergic alpha1 receptor in rat cerebral cortex
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Intermediate |
Publication
New 5-HT1A, 5HT2A and 5HT2C receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.32 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4208744 | — | — | 1 | 7.51 |
| CHEMBL3763633 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4208744 | — | Ki | = | 31.0 | nM | 7.51 |
| CHEMBL3763633 | — | Ki | = | 76.0 | nM | 7.12 |