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Assay Detail

CHEMBL4181672

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine beta-trypsin incubated for 5 mins using BAPNA as substrate by colorimetric assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Serine protease 1 (CHEMBL3769)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.
Camarero JA.
Bioorg Med Chem Lett (2017) 27 : 5089 -5099
PubMed 29110985 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 6 10.70 10.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4217607 1 10.70
CHEMBL1801042 1 10.70
CHEMBL4210529 1 10.70
CHEMBL4217569 1 10.70
CHEMBL4212172 1 10.70
CHEMBL4211294 1 10.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4217607 Ki = 0.02 nM 10.70
CHEMBL1801042 Ki = 0.02 nM 10.70
CHEMBL4210529 Ki = 0.02 nM 10.70
CHEMBL4217569 Ki = 0.02 nM 10.70
CHEMBL4212172 Ki = 0.02 nM 10.70
CHEMBL4211294 Ki = 0.02 nM 10.70