Assay Detail
Binding
CHEMBL4182929
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Non-competitive inhibition of NDM1 in Escherichia coli BL21 (DE3) using MEPM substrate incubated for 15 mins by UV spectroscopy based L-B plot
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
NOTA analogue: A first dithiocarbamate inhibitor of metallo-β-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.27 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2005280 | — | — | 1 | 5.29 |
| CHEMBL4212352 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2005280 | — | Ki | = | 5110.0 | nM | 5.29 |
| CHEMBL4212352 | — | Ki | = | 5630.0 | nM | 5.25 |