Assay Detail
Binding
CHEMBL4184426
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CaMK2gamma/delta in neonatal rat ventricular myocytes assessed as phospholamban phosphorylation after 4 hrs by Hoechst 33342 fluorescence based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 7 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.17 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4210359 | — | — | 1 | 8.21 |
| CHEMBL4215300 | — | — | 1 | 8.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4210359 | — | EC50 | = | 6.2 | nM | 8.21 |
| CHEMBL4215300 | — | EC50 | = | 7.4 | nM | 8.13 |