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Assay Detail

CHEMBL4185210

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys(R) as substrate by fluorimetric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Schistosoma mansoni
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone deacetylase 8 (CHEMBL3797017)
Type SINGLE PROTEIN
Organism Schistosoma mansoni

Publication

Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
Hailu GS, Robaa D, Forgione M, Sippl W, Rotili D, Mai A.
J Med Chem (2017) 60 : 4780 -4804
PubMed 28241112 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2094337 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2094337 IC50 = 4300.0 nM 5.37