Assay Detail
Binding
CHEMBL4185520
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FTase isolated from human Burkitt's lymphoma cells assessed as decrease in transfer of [3H]farnesyl from [3H]farnesyl PPi to H-Ras-CVLS
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Interrogating the Roles of Post-Translational Modifications of Non-Histone Proteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.54 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54044 | — | — | 1 | 9.30 |
| CHEMBL135561 | — | — | 1 | 9.30 |
| CHEMBL4218727 | — | — | 1 | 8.85 |
| CHEMBL27449 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54044 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL135561 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL4218727 | — | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL27449 | — | IC50 | = | 200.0 | nM | 6.70 |