Assay Detail
Binding
CHEMBL4186850
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.02 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4211366 | — | — | 1 | 9.00 |
| CHEMBL3586089 | — | — | 1 | 6.35 |
| CHEMBL1401388 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4211366 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3586089 | — | IC50 | = | 446.0 | nM | 6.35 |
| CHEMBL1401388 | — | IC50 | = | 1900.0 | nM | 5.72 |