Compound Detail
CHEMBL4211366
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Basic Information
| ChEMBL ID | CHEMBL4211366 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MCMLLYNXDSNKTO-PALXJHBUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
352.5
MW (Da)
2.65
ALogP
4
HBA
1
HBD
45.5
PSA (Ų)
0.87
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Menin CHEMBL1615381 | IC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Menin | IC50 | = | 1.0 | nM | 9.0 | Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by flu... | 29254892 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29254892 | 10.1016/j.bmc.2017.11.045 | Menin | 1 |
Data from ChEMBL 36 via Core Engine