Assay Detail
Functional
CHEMBL4186858
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at P2Y2 receptor in NG108-15 cells (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NG108-15 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Current knowledge on the nucleotide agonists for the P2Y2 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.33 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14249 | ADENOSINE TRIPHOSPHATE | 2.0 | 1 | 6.75 |
| CHEMBL336296 | URIDINE TRIPHOSPHATE | 3.0 | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14249 | ADENOSINE TRIPHOSPHATE | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL336296 | URIDINE TRIPHOSPHATE | EC50 | = | 1250.0 | nM | 5.90 |