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Assay Detail

CHEMBL4186981

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ADMET
Toxicity in Nicotiana tabacum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Nicotiana tabacum
Confidence 1 — Organism
Curated By Intermediate

Target

Nicotiana tabacum (CHEMBL613059)
Type ORGANISM
Organism Nicotiana tabacum

Publication

An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold.
Cherukupalli S, Hampannavar GA, Chinnam S, Chandrasekaran B, Sayyad N, Kayamba F, Reddy Aleti R, Karpoormath R.
Bioorg Med Chem (2018) 26 : 309 -339
PubMed 29273417 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.38 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2360799 1 6.70
CHEMBL4209910 1 6.30
CHEMBL4202508 1 6.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2360799 IC50 = 200.0 nM 6.70
CHEMBL4209910 IC50 = 500.0 nM 6.30
CHEMBL4202508 IC50 = 730.0 nM 6.14