Assay Detail
Binding
CHEMBL4188533
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Inhibition of prolyl oligopeptidase (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis of polyozellin, a prolyl oligopeptidase inhibitor, and its structural revision.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.80 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209844 | — | — | 1 | 6.02 |
| CHEMBL458248 | POLYOZELLIN | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209844 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL458248 | POLYOZELLIN | IC50 | = | 2720.0 | nM | 5.57 |