Assay Detail
Binding
CHEMBL4188534
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Flavobacterium POP preincubated for 5 mins followed by Z-Gly-Pro-pNA substrate measured after 30 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Flavobacterium |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Prolyl oligopeptidase family protein (CHEMBL4295533) ↗| Type | SINGLE PROTEIN |
| Organism | Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) |
Publication
Synthesis of polyozellin, a prolyl oligopeptidase inhibitor, and its structural revision.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.02 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4214751 | — | — | 1 | 6.11 |
| CHEMBL458248 | POLYOZELLIN | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4214751 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL458248 | POLYOZELLIN | IC50 | = | 1200.0 | nM | 5.92 |