Assay Detail
Binding
CHEMBL4189637
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human meprin beta expressed in baculovirus infected insect cells using N-benzoyl-L-tyrosyl-p-aminobenzoic acid as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.42 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | — | 1 | 5.70 |
| CHEMBL311932 | — | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL311932 | — | Ki | = | 7400.0 | nM | 5.13 |