Assay Detail
Functional
CHEMBL4191339
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Antiviral activity against VSV-G pseudotyped Influenza A virus infected in human SupT1 cells after 48 hrs by firefly luciferase reporter gene assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Stachybotrysins A-G, Phenylspirodrimane Derivatives from the Fungus Stachybotrys chartarum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.54 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 8.70 |
| CHEMBL4218326 | — | — | 1 | 4.91 |
| CHEMBL4217807 | — | — | 1 | 4.91 |
| CHEMBL4210446 | — | — | 1 | 4.91 |
| CHEMBL4062792 | — | — | 1 | 4.91 |
| CHEMBL4214852 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL4218326 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL4217807 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL4210446 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL4062792 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL4214852 | — | IC50 | = | 12400.0 | nM | 4.91 |