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Assay Detail

CHEMBL4191348

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC1 (unknown origin) using H3(1 to 21)K9 after 60 mins by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone deacetylase 1 (CHEMBL325)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Bioactive Glycosides from the Twigs of Litsea cubeba.
Wang LY, Chen MH, Wu J, Sun H, Liu W, Qu YH, Li YC, Wu YZ, Li R, Zhang D, Wang SJ, Lin S.
J Nat Prod (2017) 80 : 1808 -1818
PubMed 28541690 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.39 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2336751 1 5.44
CHEMBL4213781 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2336751 IC50 = 3600.0 nM 5.44
CHEMBL4213781 IC50 = 4600.0 nM 5.34