Assay Detail
Binding
CHEMBL4194482
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Candida albicans ATCC 90028 NMT using GLTISKLFRR-NH2 as substrate assessed as reduction in [3H]-myristoylated peptide reaction product formation preincubated with substrate for 10 mins followed by enzyme addition measured after 10 mins by HPLC analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Glycylpeptide N-tetradecanoyltransferase (CHEMBL3548) ↗| Type | SINGLE PROTEIN |
| Organism | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Publication
Emerging New Targets for the Treatment of Resistant Fungal Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.78 | 9.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3220375 | — | — | 1 | 9.31 |
| CHEMBL347048 | — | — | 1 | 8.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3220375 | — | IC50 | = | 0.49 | nM | 9.31 |
| CHEMBL347048 | — | IC50 | = | 5.7 | nM | 8.24 |