Assay Detail
ADMET
CHEMBL4196485
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human BJ cells after 72 hrs by CelTiter-Glo assay
72
Total Activities
72
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | BJ |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel vitexin-inspired scaffold against leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 72 | 4.29 | 4.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4218784 | — | — | 1 | 4.86 |
| CHEMBL4215634 | — | — | 1 | 4.44 |
| CHEMBL4212807 | — | — | 1 | 4.30 |
| CHEMBL4213949 | — | — | 1 | 4.17 |
| CHEMBL4209544 | — | — | 1 | 4.13 |
| CHEMBL4211234 | — | — | 1 | 4.06 |
| CHEMBL4211339 | — | — | 1 | 4.05 |
| CHEMBL4209460 | — | — | 1 | - |
| CHEMBL4212347 | — | — | 1 | - |
| CHEMBL4213120 | — | — | 1 | - |
| CHEMBL4213852 | — | — | 1 | - |
| CHEMBL4208917 | — | — | 1 | - |
| CHEMBL4207513 | — | — | 1 | - |
| CHEMBL4208488 | — | — | 1 | - |
| CHEMBL4203612 | — | — | 1 | - |
| CHEMBL4205078 | — | — | 1 | - |
| CHEMBL4216767 | — | — | 1 | - |
| CHEMBL4217304 | — | — | 1 | - |
| CHEMBL4214363 | — | — | 1 | - |
| CHEMBL4212977 | — | — | 1 | - |
| CHEMBL4208071 | — | — | 1 | - |
| CHEMBL4216450 | — | — | 1 | - |
| CHEMBL4211482 | — | — | 1 | - |
| CHEMBL4204255 | — | — | 1 | - |
| CHEMBL4215920 | — | — | 1 | - |
| CHEMBL4211526 | — | — | 1 | - |
| CHEMBL4207638 | — | — | 1 | - |
| CHEMBL4207119 | — | — | 1 | - |
| CHEMBL4202772 | — | — | 1 | - |
| CHEMBL4211996 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4218784 | — | EC50 | = | 13793.1 | nM | 4.86 |
| CHEMBL4215634 | — | EC50 | = | 36178.5 | nM | 4.44 |
| CHEMBL4212807 | — | EC50 | = | 49710.0 | nM | 4.30 |
| CHEMBL4213949 | — | EC50 | = | 68000.0 | nM | 4.17 |
| CHEMBL4209544 | — | EC50 | = | 74000.0 | nM | 4.13 |
| CHEMBL4211234 | — | EC50 | = | 86206.9 | nM | 4.06 |
| CHEMBL4211339 | — | EC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL4218261 | — | EC50 | > | 12646.6 | nM | - |
| CHEMBL4212347 | — | EC50 | > | 86206.9 | nM | - |
| CHEMBL4210902 | — | EC50 | > | 12646.6 | nM | - |
| CHEMBL4206016 | — | EC50 | > | 51724.1 | nM | - |
| CHEMBL4215320 | — | EC50 | > | 12646.6 | nM | - |
| CHEMBL4210374 | — | EC50 | > | 16094.8 | nM | - |
| CHEMBL4204580 | — | EC50 | > | 22991.4 | nM | - |
| CHEMBL4209449 | — | EC50 | > | 27586.2 | nM | - |
| CHEMBL4206533 | — | EC50 | > | 12646.6 | nM | - |
| CHEMBL4213842 | — | EC50 | > | 19543.1 | nM | - |
| CHEMBL4214451 | — | EC50 | > | 55172.4 | nM | - |
| CHEMBL4205519 | — | EC50 | > | 86206.9 | nM | - |
| CHEMBL4207771 | — | EC50 | > | 34482.8 | nM | - |
| CHEMBL4209451 | — | EC50 | > | 67241.4 | nM | - |
| CHEMBL139216 | — | EC50 | = | 371000.0 | nM | - |
| CHEMBL4205394 | — | EC50 | > | 82758.6 | nM | - |
| CHEMBL4218283 | — | EC50 | = | 139000.0 | nM | - |
| CHEMBL4204086 | — | EC50 | > | 37931.0 | nM | - |
| CHEMBL4208959 | — | EC50 | > | 34482.8 | nM | - |
| CHEMBL4217234 | — | EC50 | > | 34482.8 | nM | - |
| CHEMBL4214310 | — | EC50 | > | 29310.3 | nM | - |
| CHEMBL4212977 | — | EC50 | > | 16379.3 | nM | - |
| CHEMBL4211996 | — | EC50 | > | 53448.3 | nM | - |
| CHEMBL4202772 | — | EC50 | > | 67241.4 | nM | - |
| CHEMBL4207119 | — | EC50 | > | 36784.5 | nM | - |
| CHEMBL4207638 | — | EC50 | > | 22991.4 | nM | - |
| CHEMBL4211526 | — | EC50 | > | 48275.9 | nM | - |
| CHEMBL4215920 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL4204255 | — | EC50 | > | 32181.0 | nM | - |
| CHEMBL4211482 | — | EC50 | > | 58620.7 | nM | - |
| CHEMBL4216450 | — | EC50 | > | 54025.9 | nM | - |
| CHEMBL4208071 | — | EC50 | > | 77008.6 | nM | - |
| CHEMBL4217304 | — | EC50 | > | 26439.7 | nM | - |
| CHEMBL4214363 | — | EC50 | > | 70689.7 | nM | - |
| CHEMBL4209460 | — | EC50 | > | 39655.2 | nM | - |
| CHEMBL4213120 | — | EC50 | > | 19827.6 | nM | - |
| CHEMBL4213852 | — | EC50 | > | 40232.8 | nM | - |
| CHEMBL4208917 | — | EC50 | > | 25284.5 | nM | - |
| CHEMBL4207513 | — | EC50 | > | 32181.0 | nM | - |
| CHEMBL4208488 | — | EC50 | > | 24137.9 | nM | - |
| CHEMBL4203612 | — | EC50 | > | 19543.1 | nM | - |
| CHEMBL4205078 | — | EC50 | > | 86206.9 | nM | - |
| CHEMBL4216767 | — | EC50 | > | 24137.9 | nM | - |