Assay Detail
Functional
CHEMBL4197343
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Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of 20-epi-amino-20-deoxysalinomycin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.68 | 8.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4214392 | — | — | 1 | 8.07 |
| CHEMBL4202862 | — | — | 1 | 7.98 |
| CHEMBL4207736 | — | — | 1 | 7.80 |
| CHEMBL4206146 | — | — | 1 | 7.77 |
| CHEMBL4208987 | — | — | 1 | 7.77 |
| CHEMBL1208572 | SALINOMYCIN | 2.0 | 1 | 6.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4214392 | — | IC50 | = | 8.55 | nM | 8.07 |
| CHEMBL4202862 | — | IC50 | = | 10.37 | nM | 7.98 |
| CHEMBL4207736 | — | IC50 | = | 15.82 | nM | 7.80 |
| CHEMBL4206146 | — | IC50 | = | 17.1 | nM | 7.77 |
| CHEMBL4208987 | — | IC50 | = | 17.12 | nM | 7.77 |
| CHEMBL1208572 | SALINOMYCIN | IC50 | = | 195.0 | nM | 6.71 |