Assay Detail
Binding
CHEMBL4197653
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting method
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 9.29 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085528 | — | — | 1 | 10.00 |
| CHEMBL2367604 | — | — | 1 | 9.77 |
| CHEMBL289683 | — | — | 1 | 9.49 |
| CHEMBL297428 | — | — | 1 | 9.39 |
| CHEMBL4210742 | — | — | 1 | 9.33 |
| CHEMBL4207167 | — | — | 1 | 9.19 |
| CHEMBL55033 | — | — | 1 | 9.11 |
| CHEMBL2367916 | — | — | 1 | 8.96 |
| CHEMBL461229 | — | — | 1 | 8.92 |
| CHEMBL2367918 | — | — | 1 | 8.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085528 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL2367604 | — | Ki | = | 0.17 | nM | 9.77 |
| CHEMBL289683 | — | Ki | = | 0.32 | nM | 9.49 |
| CHEMBL297428 | — | Ki | = | 0.41 | nM | 9.39 |
| CHEMBL4210742 | — | Ki | = | 0.47 | nM | 9.33 |
| CHEMBL4207167 | — | Ki | = | 0.64 | nM | 9.19 |
| CHEMBL55033 | — | Ki | = | 0.78 | nM | 9.11 |
| CHEMBL2367916 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL461229 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL2367918 | — | Ki | = | 1.8 | nM | 8.74 |