Assay Detail
Binding
CHEMBL4197656
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from MOR in guinea pig brain membranes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.63 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4215981 | — | — | 1 | 8.96 |
| CHEMBL4204304 | — | — | 1 | 8.72 |
| CHEMBL4208635 | — | — | 1 | 8.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4215981 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL4204304 | — | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL4208635 | — | Ki | = | 6.1 | nM | 8.21 |