Assay Detail
Binding
CHEMBL4197665
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]naltrindole from DOR in monkey brain cortex membranes
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca mulatta |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
G_PROTEIN_RECEP_F1_2 domain-containing protein (CHEMBL4295544) ↗| Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
Publication
Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.11 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4204891 | — | — | 1 | 8.38 |
| CHEMBL98883 | — | — | 1 | 8.26 |
| CHEMBL4207341 | — | — | 1 | 8.24 |
| CHEMBL4209962 | — | — | 1 | 8.00 |
| CHEMBL4214248 | — | — | 1 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4204891 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL98883 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL4207341 | — | Ki | = | 5.8 | nM | 8.24 |
| CHEMBL4209962 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL4214248 | — | Ki | = | 21.0 | nM | 7.68 |