Assay Detail
Functional
CHEMBL4197978
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.32 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18442 | PLERIXAFOR | 4.0 | 1 | 8.52 |
| CHEMBL4203766 | — | — | 1 | 6.84 |
| CHEMBL28967 | — | — | 1 | 6.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18442 | PLERIXAFOR | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4203766 | — | EC50 | = | 144.0 | nM | 6.84 |
| CHEMBL28967 | — | EC50 | = | 248.0 | nM | 6.61 |