Assay Detail
Functional
CHEMBL4197979
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 assessed as inhibition of virus induced cytopathic effect
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.48 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL565514 | — | — | 1 | 9.00 |
| CHEMBL585013 | — | — | 1 | 8.40 |
| CHEMBL477121 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL565514 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL585013 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL477121 | — | EC50 | = | 9.0 | nM | 8.05 |