Assay Detail
Functional
CHEMBL4197980
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus induced cytopathic effect after 5 days by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.53 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3780418 | — | — | 1 | 8.17 |
| CHEMBL2170300 | — | — | 1 | 7.71 |
| CHEMBL4218910 | — | — | 1 | 7.36 |
| CHEMBL4214039 | — | — | 1 | 6.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3780418 | — | EC50 | = | 6.7 | nM | 8.17 |
| CHEMBL2170300 | — | EC50 | = | 19.3 | nM | 7.71 |
| CHEMBL4218910 | — | EC50 | = | 43.6 | nM | 7.36 |
| CHEMBL4214039 | — | EC50 | = | 134.3 | nM | 6.87 |