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Assay Detail

CHEMBL4199256

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human GSTP1-1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glutathione S-transferase P (CHEMBL3902)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.
Xie Y, Dahlin JL, Oakley AJ, Casarotto MG, Board PG, Baell JB.
J Med Chem (2018) 61 : 7448 -7470
PubMed 29652143 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47 ALPHA-TOCOPHEROL 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47 ALPHA-TOCOPHEROL IC50 = 500.0 nM 6.30