Assay Detail
Binding
CHEMBL4199351
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]LSD from human 5-HT1D receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of β-Arrestin Biased Ligands of 5-HT7R.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.37 | 6.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4215875 | — | — | 1 | 6.83 |
| CHEMBL4210782 | — | — | 1 | 6.78 |
| CHEMBL4209274 | — | — | 1 | 6.20 |
| CHEMBL4207884 | — | — | 1 | 5.67 |
| CHEMBL4218672 | — | — | 1 | - |
| CHEMBL4218801 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4215875 | — | Ki | = | 147.0 | nM | 6.83 |
| CHEMBL4210782 | — | Ki | = | 165.0 | nM | 6.78 |
| CHEMBL4209274 | — | Ki | = | 636.0 | nM | 6.20 |
| CHEMBL4207884 | — | Ki | = | 2112.0 | nM | 5.67 |
| CHEMBL4218672 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4218801 | — | Ki | > | 10000.0 | nM | - |