Assay Detail
Binding
CHEMBL4201484
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Ebola virus Sudan envelope glycoprotein-mediated cell entry in human HuH7 cells treated with 30 mins pre-treated pseudovirus/compopund mixture and measured after 72 hrs by luciferase reporter assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Ebolavirus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Envelope glycoprotein (CHEMBL4105829) ↗| Type | SINGLE PROTEIN |
| Organism | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus) |
Publication
De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.99 | 5.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4206744 | — | — | 1 | 5.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4206744 | — | EC50 | = | 1020.0 | nM | 5.99 |